Downregulation of Cyclophilin A by siRNA diminishes non-small cell lung cancer cell growth and metastasis via the regulation of matrix metallopeptidase 9
Abstract Background Cyclophilin A (CypA) is a cytosolic protein possessing peptidyl-prolyl isomerase activity that was recently reported to be overexpressed in several cancers.Here, we explored the biology and molecular mechanism of CypA in non-small cell lung cancer (NSCLC).Methods The expression of CypA in human NSCLC cell lines was Toddler Botto